Bio
Senior researcher at Institut de Recerca i Innovació en Salut (IRIS) and Associate Professor at Barcelona Tech (UPC), specialization in automatic control engineering at the Graduate and Master’s levels and biomedical signal processing and modeling at PhD level. She is also member of the Bioinformatics and Biomedical Signals Laboratory (B2SLab) research group at the UPC and CIBER of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN). Her main research focuses on the complexity and time-frequency analysis to the recovery of the clinically useful hidden information in cardiac, respiratory and brain signals, and on the identification and simulation of their involved physiological control mechanisms.
Doctoral Thesis supervisor
John Bustamante Osorno, (1995). “Análisis del flujo transmitral mediante el modelado y la simulación por computador”, Universitat Politècnica de Catalunya – co-supervised with Dr. Xavier Borrás from Universidad Autónoma.de Barcelona.
Raúl Carvajal Valdés, (1999). “Análisis de complejidad de la variabilidad de intervalos característicos del electrocardiograma”, Universitat Politècnica de Catalunya.
Pablo Guillén Rondón, (2002). “Análisis de la dinámica no lineal y cambios de complejidad en la variabilidad del ritmo cardiaco y en señales electroencefalográficas”, Universitat Politècnica de Catalunya
Manuel Eduardo Palacios Muñoz, (2007). “Caracterización de la variabilidad del ritmo cardíaco mediante modelos ocultos de Markov”, Universitat Politècnica de Catalunya.
Pablo Martínez Váquez, (2010). “Robust multi-command BCI systems based on steady state visual evoked potentials”, Universitat Politècnica de Catalunya – co-supervised with Dr. Andrzej Cichocki from RIKEN Brain Science Institute.
Jose Fernando Valencia Murillo, (2010). “Estimación de la complexitat de la variabilidad del ritmo cardiaco mediante técnicas de la dinámica no lineal en patologías cardiacas”, Universitat Politècnica de Catalunya.
Umberto Melia, (2014). “Representation and information theory for the analysis of eeg signals to assess different states of consciousness”, Universitat Politècnica de Catalunya.
Publications in journals
A possibly incomplete and malformatted list of publications is included below:
20231 publications
Development of an expert model for the diagnosis of inherited kidney diseases
Fayos de Ariz'on, L. and Viera, E. and Furlano, M. and Vallverdu, M. and Melissa, T. and Guirado, L. and Le'on Carrasco, R. and Perera, A. and Torra, R.
Nephrology dialysis transplantation, 38, Supplement_1 · 2023Link
20221 publications
Assessing rheoencephalography dynamics through analysis of the interactions among brain and cardiac networks during general anesthesia
Gonz'alez, C. and Garcia, G. and Jensen, E.W and Vallverdu, M.
Frontiers in Network Physiology, 2 · 2022DOI · Link
20211 publications
Time-delay selection in poincar'e plot: assessing sedation-analgesia levels with eeg signals Selecci'on del tiempo de retardo en el gr'afico de poincar'e: Medici'on de los niveles de sedaci'on y analgesia con se~nales eeg
Bolanos , J. and Valencia, J. and Vallverdu, M. and Valencia , D. and Borrat, X. and Garnb'us, P.
Ingeniare, 29, 1 · 2021Link
20194 publications
Entropy measures as descriptors to identify apneas in rheoencephalographic signals
Gonz'alez Piju'an, C. and Jensen, E.W. and Gambus, P.L. and Vallverdu, M.
Entropy (Basel), 21, 6 · 2019Link
Human emotion characterization by heart rate variability analysis guided by respiration
Valderas, M. and Bolea , J. and Orini, M. and Laguna, P. and Vallverdu, M. and Bail'on, R.
IEEE journal of biomedical and health informatics, 23, 6 · 2019Link
Mutual information between heart rate variability and respiration for emotion characterization
Valderas, M. and Bolea , J. and Laguna, P. and Bail'on, R. and Vallverdu, M.
Physiological measurement, 40, 8 · 2019DOI · Link
Refined multiscale entropy using fuzzy metrics: validation and application to nociception assessmentt
Valencia, J. and Bolanos , J. and Vallverdu, M. and Jensen, E.W. and Porta, A. and Gambus, P.
Entropy (Basel), 21, 7 · 2019Link
20182 publications
Gonz'alez Piju'an, C. and Jensen, E.W. and Gambus, P.L. and Vallverdu, M.
PloS one, 13, 12 · 2018DOI · Link
Novel characterization method of impedance cardiography signals using time-frequency distributions
Escriv'a, J. and Pan, Y. and Ge, S. and Jensen, E.W. and Vallverdu, M.
Medical and biological engineering and computing, 56, 10 · 2018DOI · Link
20171 publications
Assessment of heart rate variability during an endurance mountain trail race by multi-scale entropy analysis
Vallverdu, M. and Ruiz, A. and Roca, E. and Caminal, P. and Rodr'iguez, F. and Irurtia-Amigo, A. and Perera, A.
Entropy (Basel), 19, 12 · 2017Link
20164 publications
Advanced Signal Processing on Brain Event-Related Potentials
Melia, U. and Vallverdu, M.
Clinical neurophysiology, 127 · 2016Link
Assessment of nociceptive responsiveness levels during sedation-analgesia by entropy analysis of EEG
Valencia, J. and Melia, U. and Vallverdu, M. and Borrat, X. and Jospin, M. and Jensen, E.W and Porta, A. and Gambus, P. and Caminal, P.
Entropy (Basel), 18, 3 · 2016Link
Comparison of the qCON and qNOX indices for the assessment of unconsciousness level and noxious stimulation response during surgery
Melia, U. and Gabarr'on, E. and Agust'i, M. and Souto, N. and Pineda, P. and Fontanet, J. and Vallverdu, M. and Jensen, E.W. and Gambus, P.
Journal of clinical monitoring and computing · 2016DOI · Link
Protocol for regional implementation of collaborative lung function testing
Vargas, C.L. and Burgos, F. and Cano, I. and Blanco, I. and Caminal, P. and Escarrabill, J. and Gallego, C. and Llauger, M. and Miralles, F. and Solans, O. and Vallverdu, M. and Velickovski , F. and Roca, J.
Npj primary care respiratory medicine, 26, 16024 · 2016Link
20157 publications
Characterization of daytime sleepiness by time-frequency measures of EEG signals
Guaita, M. and Melia, U. and Vallverdu, M. and Caminal, P. and Vilaseca, I. and Monserrat, J. and Gaig, C. and Claria, F and Salamero, M. and Santamaria, J.
Journal of Medical and Biological Engineering, 35, 3 · 2015Link
Evaluation of acceleration and deceleration cardiac processes using phase-rectified signal averaging in healthy and idiopathic dilated cardiomyopathy subjects
Bas, R. and Vallverdu, M. and Valencia, J. and Voss, A. and de Luna, A. B. and Caminal, P.
Medical engineering and physics, 37, 2 · 2015Link
Methods in brain connectivity. Inference through multivariate time series analysis / Koichi Sameshima, Luiz Antonio Baccal'a. Frontiers in neuroengineering. Boca Raton, FL, USA: CRC Press, Taylor & Francis Group [ISBN 978-1-43984-5721]
Melia, U. and Vallverdu, M.
Clinical neurophysiology, 126, 5 · 2015Link
Mutual information measures applied to EEG signals for sleepiness characterization
Melia, U. and Guaita, M. and Vallverdu, M. and Embid, C. and Vilaseca, I. and Salamero, M. and Santamaria, J.
Medical engineering and physics, 37, 3 · 2015Link
Prediction of nociceptive responses during sedation by linear and non-linear measures of EEG signals in high frequencies
Melia, U. and Vallverdu, M. and Borrat, X. and Jospin, M. and Valencia, J. and Jensen, E.W and Gambus, P. and Caminal, P.
PloS one, 10, 4 · 2015Link
Regularity of cardiac rhythm as a marker of sleepiness in sleep disordered breathing
Guaita, M. and Melia, U. and Vallverdu, M. and Caminal, P. and Vilaseca, L. and Montserrat, J. and Gaig, C. and Salamero, M. and Santamaria, J.
PloS one · 2015DOI · Link
Symbolic dynamics to discriminate healthy and ischaemic dilated cardiomyopathy populations: An application to the variability of heart period and QT interval
Valencia, J. and Vallverdu, M. and Rivero, I. and Voss, A. and de Luna, A. B. and Porta, A. and Caminal, P.
Philosophical transactions of the Royal Society A. Mathematical physical and engineering sciences, 373, 2034 · 2015Link
20147 publications
Algorithm for automatic forced spirometry quality assessment: Technological developments
Melia, U. and Burgos, F. and Vallverdu, M. and Velickovski , F. and LLuch-Ariet, M. and Roca, J. and Caminal, P.
PloS one, 9, 12 · 2014DOI · Link
Auditory and nociceptive stimuli responses in the electro-encephalogram : a non-linear measures and time-frequency representation based analysis
Melia, U. and Vallverdu, M. and Claria, F and Valls-Sol'e, J. and Caminal, P.
Methods of information in medicine, 53, 4 · 2014Link
Clinical decision support system to enhance quality control of forced spirometry using information and communication technologies
Burgos, F. and Melia, U. and Vallverdu, M. and Velickovski , F. and Lluch-Ariet, M. and Caminal, P. and Roca, J.
JMIR Medical Informatics, 2, 2 · 2014Link
Correntropy measures to detect daytime sleepiness from EEG signals
Melia, U. and Guaita, M. and Vallverdu, M. and Montserrat, J. and Vilaseca, I. and Salamero, M. and Gaig, C. and Caminal, P. and Santamaria, J.
Physiological measurement, 35, 10 · 2014Link
Filtering and thresholding the analytic signal envelope in order to improve peak and spike noise reduction in EEG signals
Melia, U. and Claria, F and Vallverdu, M. and Caminal, P.
Medical engineering and physics, 36, 4 · 2014Link
Measuring instantaneous and spectral information entropies by shannon entropy of choi-williams distribution in the context of electroencephalography
Melia, U. and Claria, F and Vallverdu, M. and Caminal, P.
Entropy (Basel), 16, 5 · 2014Link
Multiscale complexity analysis of the cardiac control identifies asymptomatic and symptomatic patients in long QT syndrome type 1
Bari, V. and Valencia, J. and Vallverdu, M. and Girardengo, G. and Marchi, A. and Bassani, T. and Caminal, P. and Cerutti, S. and George Jr, A. and Brink , P.A. and Crotti, L. and Schwartz, P.J. and Porta, A.
PloS one, 9, 4 · 2014DOI · Link
20133 publications
Effect of genetic regions on the correlation between single point mutation variability and morbidity
Brunel, H. and Gallardo, J. and Vallverdu, M. and Caminal, P. and Perera, A.
Computers in biology and medicine, 43, 5 · 2013
Ischemic risk stratification by means of multivariate analysis of the heart rate variability
Valencia, J. and Vallverdu, M. and Voss, A. and Porta, A. and V'azquez, R. and Caminal, P. and de Luna, A. B.
Physiological measurement, 34, 3 · 2013Link
Short-term vs.long-term heart rate variability in ischemic cardiomyopathy risk stratification
Voss, A. and Schroeder, R. and Vallverdu, M. and Schulz, S. and Cygankiewicz, I. and V'azquez, R. and de Luna, A. B. and Caminal, P.
Frontiers in physiology, 4, 364 · 2013
20124 publications
Assessment of autonomic control of the heart during transient myocardial ischemia
Gomis, P. and Caminal, P. and Vallverdu, M. and Warren, S. and Stein, P. and Wagner, G.
Journal of electrocardiology, 45, 1 · 2012Link
Choi-Williams distribution to describe coding and non-coding regions in primary transcript pre-mRNA
Melia U. and Vallverdu, M. and Claria, F and Gallardo, J. and Perera, A. and Caminal, P.
Journal of Medical and Biological Engineering · 2012Link
High quality spirometry across the healthcare system
Burgos, F. and Vallverdu, M. and Galdiz , B. and Gallego , C. and Castillo, D. and Ayza, J. and Caminal, P. and Escarrabill , J. and Roca, J.
American journal of respiratory and critical care medicine, 185 · 2012Link
Long-term versus short-term heart rate variability analyses for risk stratification in ischemic heart failure patients
Schroeder, R. and Caminal, P. and Vallverdu, M. and Cygankiewicz, I. and Brunel, H. and V'azquez Garc'ia R. and de Luna, A. B. and Voss, A.
Biomedizinische technik, 57 · 2012Link
20112 publications
Characterization of the cerebral activity by time-frequency representation of evoked EEG potentials
Claria, F. and Vallverdu, M. and Riba, J. and Romero, S. and Caminal, P.
Physiological measurement, 32, 8 · 2011
Computational haemodynamic model for study of calculated mitral valve area
Bustamante, J. and Vallverdu, M. and Dr. Borr'as P'erez
International journal of biomedical engineering and technology, 5, 2/3 · 2011
20104 publications
Computational detection of transcription factor binding sites through differential R'enyi entropy
Maynou, J. and Gallardo, J. and Vallverdu, M. and Caminal, P. and Perera, A.
IEEE transactions on information theory, 52, 2 · 2010Link
MISS: a non-linear methodology based on mutual information for genetic association studies in both population and sib-pairs analysis
Brunel, H. and Gallardo, J. and Buil, J. and Vallverdu, M. and Soria, J. and Caminal, P. and Perera, A.
Bioinformatics, 26, 15 · 2010
Segmented Symbolic Dynamics for Risk Stratification in Patients with Ischemic Heart Failure, Cardiovascular Engineering and Technology
Voss, A. and Schroeder, R. and Caminal, P. and Vallverdu, M. and Brunel, H. and Cygankiewicz, I. and V'azquez, R. and de Luna, A. B.
Cardiovascular engineering and technology, 1, 4 · 2010Link
Symbolic dynamic analysis of relations between cardiac and breathing cycles in patients on weaning trials
Caminal, P. and Giraldo, B. and Vallverdu, M. and Benito, S. and Schroeder, R. and Voss, A.
Annals of biomedical engineering · 2010Link
20094 publications
Characterization of the nonlinear content of the heart rate dynamics during myocardial ischemia
Benitez, R. and Alvarez-Lacalle, E. and Echebarria, B. and Gomis, P. and Vallverdu, M. and Caminal, P.
Medical engineering and physics, 31, 6 · 2009Link
Complexity of the Short-Term Heart-Rate Variability Using Entropy Rates to Improve Risk Stratification to Predict Cardiac Mortality
Valencia, J. and Vallverdu, M. and Schroeder, R. and Voss, A. and Vazquez, R. and de Luna, A. B. and Caminal, P.
IEEE engineering in medicine and biology magazine, 28, 6 · 2009
Dimensionality reduction oriented toward the feature visualization for ischemia detection
Delgado-Tejos, E. and Perera, A. and Vallverdu, M. and Caminal, P. and Castellanos Dominguez, G.
IEEE transactions on information technology in biomedicine, 13, 4 · 2009Link
Refined multiscale entropy: application to 24-h Holter recordings of heart period variability in healthy and aortic stenosis subjects
Valencia, J. and Porta, A. and Vallverdu, M. and Claria, F and Baranowski, R. and Orlowska-Baranowska, E. and Caminal, P.
IEEE transactions on biomedical engineering, 56, 9 · 2009
20085 publications
DNA Binding Site Characterization by Means of R'enyi Entropy Measures on Nucleotide
Perera, A. and Vallverdu, M. and Claria, F and Caminal, P.
IEEE transactions on nanobioscience, 7, 2 · 2008
Effects of propofol anesthesia on nonlinear properties of EEG: Lyapunov exponents and short-term predictability
Roca-Gonz'alez, J. and Vallverdu, M. and Caminal, P. and Mart'inez-Gonzalez, F. and Roca-Dorda, J. and 'Alvarez, J.
IFMBE proceedings, 4 · 2008
Effects of propofol anesthesia on nonlinear properties of EEG: Time-lag and embedding dimension
Roca-Gonz'alez, J. and Vallverdu, M. and Caminal, P. and Mart'inez-Gonzalez, F. and Roca-Dorda, J. and 'Alvarez, J.
IFMBE proceedings, 4 · 2008
Heart rate turbulence predicts all-cause mortality and sudden death in congestive heart failure patients
Cygankiewicz, I. and Zareba, W. and Vazquez, R. and Vallverdu, M. and Gonzalez, J. and Valdes, M. and Almendral, J. and Cinca, J. and Caminal, P. and de Luna, A. B.
Heart rhythm, 5, 8 · 2008
Sympatho-vagal activity described by the nonlinear dynamics of the heart rate variability
Claria, F and Vallverdu, M. and Baranowski, R. and Chojnowska, L. and Caminal, P.
Physiological measurement, 29, 3 · 2008
20075 publications
Changes of autonomic information flow due to idiopathic dilated cardiomyopathy
Palacios, M. and Friedrich, H. and Christine, G. and Vallverdu, M. and de Luna, A. B. and Caminal, P. and Hoyer, D.
Physiological measurement, 28 · 2007
Detrended fluctuation analysis of EEG as a measure of depth of anesthesia
Jospin, M. and Caminal, P. and Jensen, E. and Litvan, H. and Vallverdu, M. and Struys, M. and Vereecke, H. and Kaplan, D.
IEEE transactions on biomedical engineering, 54, 5 · 2007
Gene-phenotype association using mutual information-based cluster analysis
Buil Demur, A. and Perera, A. and Brunel, H. and Souto, J. and Fontcuberta, J. and Vallverdu, M. and Soria, J. and Caminal, P.
Genetic epidemiology, 31, 6 · 2007Link
Interactions between short-term and long-term cardiovascular control mechanisms - art. no. 015110
Hoyer, D. and Frank, B. and G"otze, C. and Stein, P.K. and Zebrowski, J.J. and Baranowski, R. and Palacios, M. and Vallverdu, M. and Caminal, P. and de Luna, A. B. and Schmidt, H. and Schmidt, G.
Chaos (Woodbury, N.Y.), 17, 1 · 2007
Searching for master regulators of transcription in a human gene expression data set
Buil Demur, A. and Perera, A. and Souto, R. and Peralta, J. and Almasy, L. and Vallverdu, M. and Caminal, P. and Soria, J.
BMC proceedings (Online), 1, (Suppl 1) · 2007Link
20066 publications
An'alisis fractal del control auton'omico del ritmo cardiaco durante oclusi'on coronaria
Gomis, P. and Caminal, P. and Vallverdu, M.
Revista iberoamericana de automatica e informatica industrial, 3, 2 · 2006Link
Complex autonomic dysfunction in cardiovascular, intensive care, and schizophrenic patients assessed by autonomic information flow
Hoyer, D. and Frank, B. and G"ozte, C. and Schmidt, H. and Baranowski, R. and Zebrowski, J. and Vallverdu, M. and Caminal, P. and de Luna, A. B.
Biomedizinische technik, 51, 4 · 2006
Compression entropy contribuyes to risk stratification in patients with cardiomyopathy
Truebner, S. and Cygankiewicz, I. and Schroeder, R. and Baumert, M. and Vallverdu, M. and Caminal, P. and Vazquez, R. and de Luna, A. B. and Voss, A.
Biomedizinische technik, 51, 2 · 2006
Hidden Markov Models Based on Symbolic Dynamics for Statistical Modeling of Cardiovascular Control in Hypertensive Pregnancy Disorders
Vallverdu, M. and Caminal, P.
IEEE transactions on biomedical engineering, 53 · 2006
Non-linear dynamic analysis of the cardiac rhythm during transient myocardial ischemia
Gomis, P. and Caminal, P. and Vallverdu, M. and Warren, S. and Wagner, G.
Biomedizinische technik, 51, 4 · 2006
Relation of Heart Rate Turbulence to Severity of Heart Failure
Cygankiewicz, I. and Zareba, W. and Vazquez, R. and Vallverdu, M. and Cino, J. and Cinca, J. and Almendral, J. and Gonzalez, J. and Macaya, C. and Valdes, M. and Caminal, P. and de Luna, A. B.
American journal of cardiology, 98, 12 · 2006
20053 publications
Correlation dimension analysis of heart rate variability in patients with dilated cardiomyopathy
Carvajal, R. and Voss, A. and Wessel, N. and Vallverdu, M. and Caminal, P.
Computer methods and programs in biomedicine, 78 · 2005
Dynamics of ventricular repolarization in patients with dilated cardiomyopathy versus normal subjects
Alonso, J. and Mart'inez, P. and Vallverdu, M. and Cygankiewicz, I. and Pitzalis, M. and Bay'es-Genis, A. and Cinca, J. and Rizzon, P. and Caminal, P. and Zareba, W. and de Luna, A. B.
Annals of noninvasive electrocardiology, 10, 2 · 2005
Optimazed Symbolic Dynamics approach for the analysis of the respiratory pattern
Caminal, P. and Vallverdu, M. and Giraldo, B. and Benito, S. and V'azquez, G. and Voss, A.
IEEE transactions on biomedical engineering, 52, 1 · 2005
20042 publications
Estimating the respiratory pattern variability by symbolic dynamics
Caminal, P. and Mateu, J. and Vallverdu, M. and Giraldo, B. and Benito, S. and Voss, A.
Methods of information in medicine, 43 · 2004
Variability analysis of the respiratory volume based on nonlinear prediction methods
Caminal, P. and Domingo, L. and Giraldo, B. and Vallverdu, M. and Benito, S. and V'azquez, G. and Kaplan, D.
Medical and biological engineering and computing, 42 · 2004
20031 publications
Modeling and simulation of the central nervous system control with generic fuzzy models
Nebot, A. and Mugica, F. and Cellier, F. and Vallverdu, M.
Simulation. Transactions of the Society for Modeling and Simulation International, 79, 11 · 2003DOI · Link
20022 publications
Analysis of the RR signal by time-frequency representation: Effects of the myocardial Ischemia location
Claria, F and Vallverdu, M. and Caminal, P.
IEEE engineering in medicine and biology magazine, 21, 4 · 2002
Dimensional analysis of heart rate variability in hypertrophic cardomyopathy patients
Carvajal, R. and Zebrowski, J. and Vallverdu, M. and Baranowski, R. and Poplawska, W. and Caminal, P.
IEEE engineering in medicine and biology magazine, 21, 4 · 2002
20002 publications
An'alisis no lineal de la variablidad de la frecuencia card'iaca
Carvajal, R. and Vallverdu, M. and Caminal, P.
Revista mexicana de ingenier'ia biom'edica, 21, 2 · 2000
Time-Frequency analysis of the RR and RT variability to stratify hipertrophic cardiomyopathy patients
Claria, F and Vallverdu, M. and Baranowsli, R. and Chojnowska, L. and Caminal, P.
Computers and biomedical research, 33, 6 · 2000
19982 publications
Mixed quantitave/qualitative modeling and simulation of the cadiovascular system
Nebot, A. and Cellier, F. and Vallverdu, M.
Computer methods and programs in biomedicine, 55, 2 · 1998
Spectral analysis of heart period variance (HPV) -a tool to stratify risk following myocardial infraction
Lang, E. and Caminal, P. and Horvath, G. and Jane, R. and Vallverdu, M. and Slezsak, I. and de Luna, A. B.
Journal of medical engineering and technology, 22, 6 · 1998
19971 publications
24th QTc analysis in sudden Death risk stratification in patients with hypertrophic cardionyopathy
Baranowski, R. and Vallverdu, M. and Jane, R. and Caminal, P. and Poplawska, W. and Malecka, L. and Chojnowska, L. and Rydlewsa-Sodowska, W. and Vinolas, X. and de Luna, A. B.
Circulation, 96, 8 · 1997
19941 publications
Cardiovascular responses to intrathoracic pressure variations in coronary disease patients: a computer simulation
Vallverdu, M. and CREXELLS, C. and Caminal, P.
Technology and health care, 2, 2 · 1994
Unknown Year2 publications
Poincar'e plot analysis of cerebral blood flow signals : feature extraction and classification methods for apnea detection
Unknown
Time-frequency features for impedance cardiography signals during anesthesia using different distribution kernels
Unknown
